For participating R+D sites, to recruit a patient to the SYNaPS Study, please complete the following steps:

1. Ensure that the patient is suitable for the study

• Lacks a genetic diagnosis
• Has an paroxysmal neurological condition such as epilepsy, headache, movement disorders, episodic ataxia, sleep disorders.

2. Provide patient with this Patient Information Leaflet :

3. Provide patient with the Consent Form for signing :

4. Take whole blood samples in 2 EDTA (purple topped) tubes and fill out the DNA Request Form.

5. Email us at ion.synapse@ucl.ac.uk and post the blood bottles together with completed consents to:

DNA Neurogenetics Lab, 6th floor,
Institute of Neurology, Queen Square,
London WC1N 3BG