I am a young Neurologist, currently working as a Clinical Research Fellow at the Rare Neurological Disease Centre of the Fondazione Policlinico A. Gemelli/Catholic University of the Sacred Heart in Rome, under the supervision of Prof. Gabriella Silvestri.
As a Specialty Registrar, I started showing interest in clinical research on rare neurological diseases, focusing on Myotonic Dystrophies, Spinocerebellar Ataxias and Hereditary Spastic Paraplegias.
In 2019, I had the opportunity to spend 6 months as a visiting fellow at the UCL Queen Square Institute of Neurology in London, in the Neurogenetics research group lead by Prof. Henry Houlden. This gave me the opportunity to dive and improve my expertise into the field of rare neurological diseases from a clinical point of view, attending both Multiple System Atrophy and Neurogenetics Clinic, and joining UCL classes and courses as well. Moreover, during my fellowship my laboratory research activity was focused on molecular screening of a newly-recognised inherited ataxia, whose acronym is CANVAS (Cerebellar Ataxia Neuropathy Vestibular Areflexia Syndrome).
This experience deeply increased my knowledge in Neurogenetics, and helped me to realise how molecular research is fundamental to understand mechanisms underlying a disease, in order to address clinical and treatment needs.
Currently, I am working on a nation-wide Italian project on the clinical aspects of SPG4, the most common pure form of autosomal dominant hereditary spastic paraplegia.