Dr Zhongbo Chen

I am currently studying for a PhD on the Leonard Wolfson Clinical Fellowship Programme under the supervision of Dr Mina Ryten, Professor Henry Houlden and Professor Nick Wood. My PhD focuses on using informatic techniques to improve our understanding of the pathophysiology underlying neurodegenerative and neurogenetic disorders such as hereditary ataxias. My project will leverage machine learning as a powerful tool to analyse and decipher hidden information within -omics data in thousands of individuals to predict pathogenic genes. Parallel to the PhD, I will gain further specialist clinical training in neurogenetics and movement disorders at Queen Square, with the aim of integrating research findings to improve patient diagnosis and care.

Prior to embarking on the fellowship, I was a Neurology Specialist Registrar at the National Hospital for Neurology and Neurosurgery and NIHR Academic Clinical Fellow in Neurology at King’s College London studying the genetics of amyotrophic lateral sclerosis and progressive supranuclear palsy. I graduated in Clinical Medicine from the University of Oxford in 2010 having completed pre-clinical studies at the University of Cambridge where my final year project investigated the electrophysiological properties of skeletal muscle fibres.

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